Test Directory

Home Test Search Results Russell Viper Venom Time (dilute)
Russell Viper Venom Time (dilute)

Justification

The presence of antiphospholipid antibodies, such as lupus anticoagulant, increases the risk of arterial thrombosis, venous thrombosis, thrombocytopenia and recurrent miscarriage. Lupus anticoagulants result in the prolongation of clotting times which correct with the addition of phospholipids.

STAT: < 24 hours (7 days a week)

Clot-based

Draw Tube: Blue Top

Sample Type: Citrated Plasma

Specimen Requirements

Sample Type Volume Required Minimum Volume Stability
PREFERRED Citrated Plasma 1mL 0.5mL Frozen (-20C): 2 weeks
Frozen (-80C): 6 months
ALTERNATIVE - - - -
REJECTION CRITERIA Thawed in transit, refrozen or clotted sample
SPECIAL INSTRUCTIONS -

General Information

METHODOLOGY Clot-based
STAT TAT < 24 hours (7 days a week)
STAT TAT Performance > 90% of results released in 24 hours 7 days a week
ROUTINE TAT < 3 days (M-F)
ALTERNATIVE NAMES dRVVT, LA screen
DESCRIPTION Russell’s Viper venom directly activates factor X, bypassing factor VII of the extrinsic pathway and the contact and antihemophilic factors of the intrinsic pathway. Therefore, the dRVVT is more specific screening test for lupus anticoagulant than aPTTs, as it is not affected by deficiencies in or specific inhibitors against Factor VII, XII, XI, IX, or VIII. When prolongations are detected in the dRVVT Screen, a dRVVT Confirm is performed and the dRVVT Ratio calculated.
LIMITATIONS -
NORMAL RANGE Screen: 28.8-41.5 secondsRatio: 0.72-1.26
ASSOCIATED TESTING -
REFERENCES -
SAMPLE REPORT Upon request
NEW YORK STATE APPROVED Yes

Test Codes

ORDER CODE P3043
CPT CODE 85613
LOINC CODE 6303-2