Factor XIII (13) Activity – Quantitative

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Justification

Factor XIII deficiency is an autosomal recessive disorder that results in internal bleeding, including brain hemorrhaging, following even mild trauma. Continued bleeding may lead to formation of large cysts that may damage bone and nerves. Infants born with Factor XIII deficiency may bleed from the umbilical cord. Affected females have high risk for miscarriage if not receiving treatment, while affected males may be sterile. Treatment includes infusion of fresh or frozen blood or Factor XIII concentrates.

STAT: < 1 week

ELISA

Draw Tube: Blue Top

Sample Type: Citrated Plasma

Specimen Requirements

	Sample Type	Volume Required	Minimum Volume	Stability
PREFERRED	Citrated Plasma	1mL	0.5mL	Frozen (-20C): 2 weeks Frozen (-80C): 6 months
ALTERNATIVE	-	-	-	-

REJECTION CRITERIA	Thawed in transit, refrozen or clotted sample
SPECIAL INSTRUCTIONS	-

General Information

METHODOLOGY	ELISA
STAT TAT	< 1 week
STAT TAT Performance	> 90% of results released in 1 week
ROUTINE TAT	< 1 week
ALTERNATIVE NAMES	F13, FXIII
DESCRIPTION	-
LIMITATIONS	-
NORMAL RANGE	-
ASSOCIATED TESTING	-
REFERENCES	-
SAMPLE REPORT	Upon request
NEW YORK STATE APPROVED	No

Test Codes

ORDER CODE	P3302
CPT CODE	85290
LOINC CODE	3241-7