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Hexagonal Phospholipid aPTT

Justification

The presence of antiphospholipid antibodies, such as lupus anticoagulant, increases the risk of arterial thrombosis, venous thrombosis, thrombocytopenia and recurrent miscarriage. Lupus anticoagulants result in the prolongation of clotting times which correct with the addition of phospholipids.

STAT: < 48 hours (M-F)

Clot-based

Draw Tube: Blue Top

Sample Type: Citrated Plasma

Specimen Requirements

Sample Type Volume Required Minimum Volume Stability
PREFERRED Citrated Plasma 1mL 0.5mL Frozen (-20C): 2 weeks
Frozen (-80C): 6 months
ALTERNATIVE - - - -
REJECTION CRITERIA Thawed in transit, refrozen or clotted sample
SPECIAL INSTRUCTIONS -

General Information

METHODOLOGY Clot-based
STAT TAT < 48 hours (M-F)
STAT TAT Performance > 90% of results released in 48 hours
ROUTINE TAT < 1 week
ALTERNATIVE NAMES Hex Phos
DESCRIPTION Hexagonal phase phospholipid (HPP) neutralization assay. Addition of HPPs neutralize the effect of lupus anticoagulant antibodies present and results in correction of the prolonged aPTT.
LIMITATIONS -
NORMAL RANGE Ratio < 11
ASSOCIATED TESTING -
REFERENCES -
SAMPLE REPORT Upon request
NEW YORK STATE APPROVED -

Test Codes

ORDER CODE P3303
CPT CODE 85730x2
LOINC CODE 3282-1