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Prolonged aPTT/PT Evaluation Work-up

Justification

To evaluate prolongations in the aPTT, Machaon utilizes three (3) different aPTT reagents: standard, lupus anticoagulant sensitive and factor sensitive (aPTT, aPTT-LA and aPTT-FS, respectively). A single aPTT reagent does not provide the range of sensitivities sufficiently suitable to characterize the various samples encountered in the clinical setting, including but not limited to anticoagulant monitoring, factor deficiency detection and lupus anticoagulant screening.

Panel Component Tests

aPTT Prothrombin Time (PT/INR) Thrombin Time Fibrinogen Activity aPTT-FS (Factor Sensitive) aPTT-LA (Lupus Sensitive) Russell Viper Venom Time (dilute) Hexagonal Phospholipid aPTT Anticardiolipin Antibody (IgG, IgM, IgA)

STAT: < 48 hours (M-F)

Clot-based, CIA

Draw Tube: Blue Top

Draw Tube: Red Top

Sample Type: Citrated Plasma and Serum

Specimen Requirements

Sample Type Volume Required Minimum Volume Stability
PREFERRED Citrated Plasma and Serum Five aliquots, 1mL each (Citrated Plasma);One aliquot, 1mL (Serum) Five aliquots, 0.5mL each (Citrated Plasma);One aliquot, 0.5mL (Serum) Frozen (-20C): 2 weeks
Frozen (-80C): 6 months
ALTERNATIVE - - - -
REJECTION CRITERIA Thawed in transit, refrozen or clotted sample
SPECIAL INSTRUCTIONS -

General Information

METHODOLOGY Clot-based, CIA
STAT TAT < 48 hours (M-F)
STAT TAT Performance > 90% of results released in 48 hours
ROUTINE TAT < 1 week
ALTERNATIVE NAMES -
DESCRIPTION -
LIMITATIONS -
NORMAL RANGE Interpretation
ASSOCIATED TESTING -
REFERENCES -
SAMPLE REPORT Upon request
NEW YORK STATE APPROVED -

Test Codes

ORDER CODE P1197
CPT CODE see reflexive tests
LOINC CODE see reflexive tests